Ontology highlight
ABSTRACT:
ORGANISM(S): Drosophila melanogaster
SUBMITTER: Alexey Pindyurin
PROVIDER: E-MEXP-864 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Pindyurin Alexey V AV Moorman Celine C de Wit Elzo E Belyakin Stepan N SN Belyaeva Elena S ES Christophides George K GK Kafatos Fotis C FC van Steensel Bas B Zhimulev Igor F IF
Journal of cell science 20070701 Pt 14
Drosophila melanogaster Suppressor of Under-Replication (SuUR) gene encodes a protein that modulates replicative properties of heterochromatin in endocycles of polytene cells. The SuUR mutation abolishes underreplication of intercalary heterochromatin and results in partial underreplication of pericentric heterochromatin. We performed a genome-wide mapping of SUUR target genes in non-polytenic Drosophila Kc cells by using the DamID approach. We show that SUUR preferentially binds genes that are ...[more]