Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of tooth germs from mouse fetuses and embryos


ABSTRACT: Study of changes in gene expression in mouse tooth germs between E15.5 and 21.5dpc

INSTRUMENT(S): ScanArray Lite [PerkinElmer]

ORGANISM(S): Mus musculus

SUBMITTER: Maria Landin 

PROVIDER: E-MEXP-947 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Changes in gene-expression during development of the murine molar tooth germ.

Osmundsen Harald H   Landin Maria A MA   From Sigurd H SH   Kolltveit Kristin M KM   Risnes Steinar S  

Archives of oral biology 20070319 9


In a matter of a few days the murine tooth germ develops into a complex, mineralized, structure. Murine 30K microarrays were used to examine gene expression in the mandibular first molar tooth germs isolated at 15.5dpc and at 2DPN. Microarray results were validated using real-time RT-PCR. The results suggested that only 25 genes (3 without known functions) exhibited significantly higher expression at 15.5dpc compared to 2DPN. In contrast, almost 1400 genes exhibited significantly (P<0.015) highe  ...[more]

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