Ontology highlight
ABSTRACT:
ORGANISM(S): Escherichia coli
SUBMITTER: Thithiwat May
PROVIDER: E-MEXP-953 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Antimicrobial agents and chemotherapy 20090831 11
Biofilms gain resistance to various antimicrobial agents, and the presence of antibiotic resistance genes is thought to contribute to a biofilm-mediated antibiotic resistance. Here we showed the interplay between the tetracycline resistance efflux pump TetA(C) and the ampicillin resistance gene (bla(TEM-1)) in biofilms of Escherichia coli harboring pBR322 in the presence of the mixture of ampicillin and tetracycline. E. coli in the biofilms could obtain the high-level resistance to ampicillin, t ...[more]