Ontology highlight
ABSTRACT:
INSTRUMENT(S): NextSeq 550
ORGANISM(S): Homo sapiens
SUBMITTER: Gray Camp
PROVIDER: E-MTAB-10037 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Fleck Jonas Simon JS Sanchís-Calleja Fátima F He Zhisong Z Santel Malgorzata M Boyle Michael James MJ Camp J Gray JG Treutlein Barbara B
Cell stem cell 20210311 6
Self-organizing tissues resembling brain structures generated from human stem cells offer exciting possibilities to study human brain development, disease, and evolution. These 3D models are complex and can contain cells at various stages of differentiation from different brain regions. Single-cell genomic methods provide powerful approaches to explore cell composition, differentiation trajectories, and genetic perturbations in brain organoid systems. However, it remains a major challenge to und ...[more]