Haematopoietic stem and progenitor cells are present in healthy gingiva tissue
Ontology highlight
ABSTRACT: Haematopoietic stem cells reside in the bone marrow where they generate the effector cells that drive immune responses. However, in response to inflammation some haematopoietic stem and progenitor cells (HSPC) are recruited to tissue sites and undergo extramedullary haematopoiesis. Contrasting this paradigm here we show, with single cell sequencing, residence and differentiation of HSPC in healthy gingiva, a key oral barrier, in the absence of overt inflammation.
INSTRUMENT(S): NextSeq 550
ORGANISM(S): Mus musculus
SUBMITTER: Leo Zeef
PROVIDER: E-MTAB-10050 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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