Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Steven Van Laere
PROVIDER: E-MTAB-1006 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Van der Auwera I I Limame R R van Dam P P Vermeulen P B PB Dirix L Y LY Van Laere S J SJ
British journal of cancer 20100727 4
<h4>Background</h4>MicroRNAs (miRNAs) are key regulators of gene expression. In this study, we explored whether altered miRNA expression has a prominent role in defining the inflammatory breast cancer (IBC) phenotype.<h4>Methods</h4>We used quantitative PCR technology to evaluate the expression of 384 miRNAs in 20 IBC and 50 non-IBC samples. To gain understanding on the biological functions deregulated by aberrant miRNA expression, we looked for direct miRNA targets by performing pair-wise corre ...[more]