Unknown,Transcriptomics,Genomics,Proteomics

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Compressed and non-compressed tissue-engineered HS-deficient and WT cartilage


ABSTRACT: Murine primary rib-cage chondrocytes (mRCs) were isolated from E15.5 WT and HS-deficient Ext1gt/gt mice and expanded for 6-7 days. Tissue-engineered cartilage was generated by a 14-day chondrogenic culture of mRCs at 5×10^5 cells per 25 µl agarose carrier. Engineered cartilage was exposed to cyclic unconfined compression for 3 hours: 10-minute cycles of dynamic unconfined compression (25 % dynamic compression at 1 Hz superimposed to 10 % static off-set) were intermitted by 10-minute breaks (10 % static off-set).

ORGANISM(S): Mus musculus

SUBMITTER: Matthias Gerstner 

PROVIDER: E-MTAB-10258 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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