Unknown,Transcriptomics,Genomics,Proteomics

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RNA-seq of human prostate cancer cell line DU145 overexpressed GADD45B against control

ABSTRACT: Chemo-resistance is the major cause of death in advanced prostate cancer (PCa), especially in metastatic PCa (mPCa). However, the molecular mechanisms behind chemo-resistance of PCa have not been clarified so far. Here we found GADD45B was significantly low expressed in metastasis PCa and it could promote chemotherapy sensitivity. So we further constructed GADD45B overexpressed cell line to investigate the possible mechanism.

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Homo sapiens

SUBMITTER: Qiong Wang

PROVIDER: E-MTAB-10704 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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RNA-seq of human prostate cancer cell line DU145 overexpressed GADD45B against control

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