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Tracing the emergence of primordial germ cells from bilaminar disc rabbit embryos and pluripotent stem cells (bulk RNA-sequencing)

ABSTRACT: Rabbit embryos, as in humans, develop as bilaminar discs at gastrulation and unlike egg cylinders as in rodents. Mammalian primordial germ cells (PGCs) in all species originate during gastrulation. We sequence the transcriptomes of rabbit embryos during gastrulation, and show that rabbit PGC (rbPGC) specification occurs at the posterior epiblast at the onset of gastrulation

INSTRUMENT(S): Illumina HiSeq 4000

ORGANISM(S): Oryctolagus cuniculus

SUBMITTER: Toshihiro Kobayashi

PROVIDER: E-MTAB-10892 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Tracing the emergence of primordial germ cells from bilaminar disc rabbit embryos and pluripotent stem cells (cell culture)

Project description:Rabbit embryos, as in humans, develop as bilaminar discs at gastrulation and unlike egg cylinders as in rodents. Mammalian primordial germ cells (PGCs) in all species originate during gastrulation. We sequence the transcriptomes of rabbit embryos during gastrulation, and show that rabbit PGC (rbPGC) specification occurs at the posterior epiblast at the onset of gastrulation

2021-10-14 | E-MTAB-10893 | biostudies-arrayexpress

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Reactive astrocytes transduce blood-brain barrier inflammation through a TNFα-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin

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