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Epigenetic comparison of human DNA in specific human tissues to human DNA in transgenic mouse tissues

ABSTRACT: This project aims to study human repetitive elements on human chromosome 21 (HsChr21) in a heterologous mouse environment (Tc1 mouse). The in vivo, HsChr21-wide enrichment of active histone modified regions (H3K4me3) and transcription factor binding sites was profiled by ChIP-seq in Human and Tc1 mouse tissue in order to determine the unbiased regulation of the human genome.

INSTRUMENT(S): Illumina Genome Analyzer II, Illumina HiSeq 2000

ORGANISM(S): Mus musculus

SUBMITTER: Michael Wilson

PROVIDER: E-MTAB-1104 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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