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PTHrP Induces STAT5 Activation, Secretory Differentiation and Mammary Tumor Progression

ABSTRACT: Parathyroid hormone-related protein (PTHrP) is required for embryonic breast development and has important functions during lactation, when it is produced by alveolar epithelial cells and secreted into the maternal circulation to mobilize skeletal calcium used for milk production. PTHrP is also produced by breast cancers and GWAS studies suggest that it influences breast cancer risk. However, the exact functions of PTHrP in breast cancer biology remain unsettled.

ORGANISM(S): Mus musculus

SUBMITTER: Martin Garcia Sola E

PROVIDER: E-MTAB-11281 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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