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2-hydroxyglutarate modulates histone methylation using both RNA/ChIP-seq

ABSTRACT: 2-hydroxyglutarate (2-HG) is an oncometabolite accumulating in certain cancers and some neurometabolic diseases. In cancers 2-HG accumulation is induced by a gain-of-function mutation in isocitrate dehydrogenase (IDH) genes, leading to conversion of alpha-ketoglutarate (a-KG) into 2-HG

INSTRUMENT(S): NextSeq 500

ORGANISM(S): Saccharomyces cerevisiae S288C

SUBMITTER: Lasse Sinkkonen

PROVIDER: E-MTAB-11328 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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