Single-cell sequencing of tissue-resident CD8+ T cells that drive compartmentalized immunopathology in the CNS
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ABSTRACT: In chronic inflammatory diseases of the central nervous system (CNS), immune cells persisting behind the blood-brain barrier are supposed to promulgate local tissue destruction. The drivers of such compartmentalized inflammation remain unclear, but tissue-resident memory T cells (TRM) represent a potentially important cellular player in this process
INSTRUMENT(S): Illumina NovaSeq 6000
ORGANISM(S): Mus musculus
SUBMITTER: Alex Yermanos
PROVIDER: E-MTAB-11511 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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