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Microarray of liver tissue from C57BL/6 mouse liver treated with ConA against untreated controls

ABSTRACT: It will be conducive to early diagnosis, appropriate treatment, and improved prognosis for AIH by a comprehensive understanding of the lncRNAs disorders. So, the characterization of these differently expressed lncRNAs, as well as the expression profiling of differently expressed of messenger RNAs, in the AIH mouse model induced by Con A with microarray chip were gained by microarray assay. Con A (15mg/kg, dissolved in pyrogen-free saline) was administrated to the mice in model group (n=4) via tail vein injection. The sham group mice (n=4) were given pyrogen-free saline alone with the same method. All mice were anesthetized lethally at 8h after the administration of Con A or pyrogen-free saline. Hepatic tissues of each mouse were harvested by surgery under low temperature and sterile conditions, and homogenized immediately for extracting total RNA with Trizol Reagent.

ORGANISM(S): Mus musculus

SUBMITTER: Yang Liu

PROVIDER: E-MTAB-11698 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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