Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

RNA-seq of lung myeloid cells from WT and Ptgs2-cKO mice


ABSTRACT: To investigate the role of the COX-2-dependent lung fibroblast program in reprogramming lung myeloid cells, we generated fibroblast-targeted Ptgs2 conditional knockout mice by crossing Pdgfra-Cre mice with Ptgs2flox/flox mice. Then we isolated two primary types of lung resident DCs-CD103+ conventional DC (cDC1) and CD11b+ conventional DC (cDC2), and lung monocytes from WT and Ptgs2 cKO mice by fluorescence-activated cell sorting and performed RNA sequencing.

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Mus musculus

SUBMITTER: Zheng Gong 

PROVIDER: E-MTAB-11888 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2022-07-19 | GSE206449 | GEO
2022-07-19 | E-MTAB-11873 | biostudies-arrayexpress
2022-08-22 | PXD026068 | Pride
2015-06-08 | E-GEOD-66899 | biostudies-arrayexpress
2021-03-21 | PXD018783 | Pride
2020-11-24 | E-MTAB-9522 | biostudies-arrayexpress
2013-12-14 | E-GEOD-53312 | biostudies-arrayexpress
2010-07-15 | GSE22011 | GEO
2021-03-21 | PXD023581 | Pride
2010-07-15 | E-GEOD-22011 | biostudies-arrayexpress