Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Host transcriptome profiling of the Lumpy Skin Disease (LSD) for resilience and susceptibility


ABSTRACT: Lumpy Skin Disease (LSD) is an endemic viral infection in Africa, newly emerging in Europe and becoming a global threat. There is host variation in response to infections in field studies and under carefully controlled artificial infections. It’s sometimes around 50% in clinical trials. This study aims to understand the mechanisms underlying this diversity and find the determinants to distinguish between susceptible (recovered) and resistant (non-recovered) animals through Differential Gene Expression (DGE) analysis. Five approximately 6-month-old male Holstein bulls were experimentally infected with LSDV. RNA sequencing was done for whole blood samples collected five days prior (pre-infection) to 3, 7, and 15 days after the infection (post-infection) challenge. After the challenge, two animals recovered, and three did not.

INSTRUMENT(S): NextSeq 500

ORGANISM(S): Bos taurus

SUBMITTER: Mohammad Hossein Banabazi 

PROVIDER: E-MTAB-12547 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2023-02-17 | E-MTAB-12608 | biostudies-arrayexpress
2021-08-11 | E-MTAB-10527 | biostudies-arrayexpress
2024-09-23 | E-MTAB-13307 | biostudies-arrayexpress
2011-04-19 | E-GEOD-28686 | biostudies-arrayexpress
2012-10-15 | E-GEOD-40396 | biostudies-arrayexpress
2019-03-21 | E-MTAB-7699 | biostudies-arrayexpress
2010-09-01 | E-GEOD-23863 | biostudies-arrayexpress
2021-05-17 | E-MTAB-10309 | biostudies-arrayexpress
2016-07-27 | E-GEOD-64456 | biostudies-arrayexpress
2014-10-24 | E-GEOD-60009 | biostudies-arrayexpress