Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Transcription profiling of flounders (Platichthys flesus) exposed to polybrominated diphenyl ethers (pentamix)

ABSTRACT: A Platichthys flesus cDNA microarray (GENIPOL) comprised of 12,700 clones, was used to determine and characterize gene expression profiles of flounders (Platichthys flesus) exposed to polybrominated diphenyl ethers (pentamix).

ORGANISM(S): Platichthys flesus

SUBMITTER: Tim Williams

PROVIDER: E-MTAB-1255 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Transcriptomic responses of European flounder (Platichthys flesus) liver to a brominated flame retardant mixture.

Williams Tim D TD Diab Amer M AM Gubbins Matt M Collins Catherine C Matejusova Iveta I Kerr Rose R Chipman James K JK Kuiper Raoul R Vethaak A Dick AD George Stephen G SG

Aquatic toxicology (Amsterdam, Netherlands) 20130729

Male European flounder (Platichthys flesus) were exposed to a technical mixture of brominated diphenyl ethers (PDBEs, DE-71, Pentamix) that had been purified to remove contaminating dioxins. Controls were exposed to carrier solvent alone. Fish were exposed to decadally increasing concentrations of Pentamix via both sediment and spiked food. The GENIPOL P. flesus cDNA microarray, differentially expressed gene profiling (DEG) and quantitative PCR were employed to detect hepatic transcriptional dif ...[more]

PMID: 23948077

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Dataset Information

Transcription profiling of flounders (Platichthys flesus) exposed to polybrominated diphenyl ethers (pentamix)

Publications

Transcriptomic responses of European flounder (Platichthys flesus) liver to a brominated flame retardant mixture.

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