Browse
Submit Data
Databases
API
Help

Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-seq of various organs of Potentilla indica and Melastoma dodencadrum Lour.

ABSTRACT: Potentilla indica and Melastoma dodecandrum lour are medicinal herbs used in traditional Chinese medicine. We sampled the plants from Nanyang Technological University's herb garden for transcriptomics analysis.

INSTRUMENT(S): NovaSeq PE150, Illumina NovaSeq 6000, Spectrum™ Plant Total RNA Kit

ORGANISM(S): Potentilla indica

SUBMITTER: Dr. Marek Mutwil

PROVIDER: E-MTAB-12682 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

Gene expression in cells encapsulated within different types of alginate microcapsules

Project description:D1 multipotent mesenchymal stromal cells (D1‐MSCs,ATCC® CRL 12424TM) and genetically modified with the lentiviral vector pSIN‐EF2‐Epo‐Pur to express erythropoietin (EPO). D1‐MSCs genetically modified to release EPO were immobilized into 3D alginatepoly‐ L‐lysine‐alginate (APA) microcapsules. Since different formulations of alginate 1.5%, poly‐L‐lysine 0.05%, alginate 0.1% and washings were designed, two types of APA microcapsules were obtained: Biological microcapsules (made of Biological formulations) and Technological microcapsules (made of Technological formulations). The expression of the cells under different conditions of these two types of microcapsules have been analyzed. The present analysis proved that the mechanical properties of the matrix in which cells are enclosed influences drastically gene expression

2017-10-30 | E-MTAB-5786 | biostudies-arrayexpress

Clinical study for detoxification and dispersal herbs combined with TACE in the treatment of unresectable liver metastasis of colorectal cancer and its correlation with exogenous microRNAs

Project description:Interventions: experimental group:detoxification and dispersal herbs combined with TACE ;control group:placebo (herb) combined with TACE Primary outcome(s): PFS Study Design: Parallel

| 2686364 | ecrin-mdr-crc

Project description:Chloroplast genomes of nine medicinal herbs

| PRJNA751140 | ENA

Genome-wide analysis of berberine chloride-responsive gene expression in HepG2 liver cell line

Project description:Berberine, an isoquinoline alkaloid isolated from many medicinal herbs such as Coptis chinensis, has a wide range of pharmacological effects. Here, we used gene expression microarray to analyze gene expression profiles of HepG2 human hepatoma cell line after berberine chloride treatment or 0.08% DMSO as control.

2013-10-02 | GSE47786 | GEO

Chlorophytum borivilianum

Project description:Annual herb of medicinal value

| PRJNA32621 | ENA

proteomics analysis haustorium development of Taxillus chinensis

Project description:Loranthus (Taxillus chinensis) is an important medicinal and parasitic plant that attacks other plants for living. To reveal the mechanisms of haustorium development, we employed an iTRAQ proteomics-based approach to identify differentially abundant proteins (DAPs) of fresh seeds (CK), baby (FB), and adult haustoria (FD).

2022-10-14 | PXD029830 | Pride

Transcriptional Profile of the Shigella flexneri Response to Berberine

Project description:Berberine is a natural isoquinoline alkaloid found in Chinese medicinal herbs which is active against a variety of microbial infections. To examine the potential effects of berberine on Shigella flexneri, a whole-genome DNA microarray was constructed and transcriptome analysis of the cellular responses of S.flexneri when exposed to Berberine Chloride (BC) was performed.

2012-03-10 | GSE16714 | GEO

Project description:Response of gut microbiota to nootropic medicinal herbs

| PRJNA988266 | ENA

MicroRNA expression profiling of hepatocellular carcinoma cell line BEL-7402 treated with baicalein

Project description:Baicalein, a purified flavonoid compound with defined chemical structure extracted from the dry roots of Scutellaria radix that is a broadly used herb in China, has been proved to possess significant anti-hepatoma activity by inhibiting cell proliferation, invasion, metastasis and inducing apoptosis, autophagy via several cancer-related signaling molecules. In recent years, emerging studies have demonstrated that Chinese medicinal herbs can exert their anti-tumor effects through targeting miRNAs，such as curcumin, camptothecin, resveratrol. However, there is still no related report about the effects of baicalein on miRNA expression profile when it exerts its inhibition on hepatoma tumor growth. To investigate whether the antitumor effect of baicalein is related to its modulation of miRNA expression in hepatocellular carcinoma (HCC), we profiled the miRNA expression in HCC cell line Bel-7402 treated with baicalein (0, 40, 80μM) for 24 hours using miRNA microarray and detected the changes by comparing the miRNA expression profile of HCC cell line Bel-7402 treated with baicalein (40 and 80 μM) and its DMSO control (0 μM). These findings suggest that modulation of miRNA expression may be an important mechanism underlying the anti-hepatoma effects of baicalein and lay the groundwork for further investigations.

2017-08-15 | GSE85511 | GEO

phyllosphere metagenome

Project description:Garden herb phyllosphere Targeted Locus (Loci)

| PRJNA273289 | ENA