Ontology highlight
ABSTRACT:
ORGANISM(S): Pseudomonas aeruginosa PAO1
SUBMITTER: Manjeet Bains
PROVIDER: E-MTAB-1276 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Fernández Lucía L Jenssen Håvard H Bains Manjeet M Wiegand Irith I Gooderham W James WJ Hancock Robert E W RE
Antimicrobial agents and chemotherapy 20120924 12
Cationic antimicrobial peptides pass across the outer membrane by interacting with negatively charged lipopolysaccharide (LPS), leading to outer membrane permeabilization in a process termed self-promoted uptake. Resistance can be mediated by the addition of positively charged arabinosamine through the action of the arnBCADTEF operon. We recently described a series of two-component regulators that lead to the activation of the arn operon after recognizing environmental signals, including low-Mg( ...[more]