Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

MBains PAO1 cprR (CP28)


ABSTRACT: Micoarrays were used to obtain gene expression in mid-log phase PAO1::cprR(PA3077) with the treatment of 12ug/ml CP28 vs mid-log phase PAO1 with the treatment of 12ug/ml CP28

ORGANISM(S): Pseudomonas aeruginosa PAO1

SUBMITTER: Manjeet Bains 

PROVIDER: E-MTAB-1276 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

altmetric image

Publications

The two-component system CprRS senses cationic peptides and triggers adaptive resistance in Pseudomonas aeruginosa independently of ParRS.

Fernández Lucía L   Jenssen Håvard H   Bains Manjeet M   Wiegand Irith I   Gooderham W James WJ   Hancock Robert E W RE  

Antimicrobial agents and chemotherapy 20120924 12


Cationic antimicrobial peptides pass across the outer membrane by interacting with negatively charged lipopolysaccharide (LPS), leading to outer membrane permeabilization in a process termed self-promoted uptake. Resistance can be mediated by the addition of positively charged arabinosamine through the action of the arnBCADTEF operon. We recently described a series of two-component regulators that lead to the activation of the arn operon after recognizing environmental signals, including low-Mg(  ...[more]

Similar Datasets

2012-03-25 | E-MTAB-1000 | biostudies-arrayexpress
2012-12-01 | E-MTAB-1170 | biostudies-arrayexpress
2012-04-19 | E-MTAB-962 | biostudies-arrayexpress
2010-08-31 | E-FPMI-21 | biostudies-arrayexpress
2012-08-22 | E-GEOD-40172 | biostudies-arrayexpress
2013-08-13 | E-GEOD-38272 | biostudies-arrayexpress
2008-12-20 | E-FPMI-18 | biostudies-arrayexpress
2011-12-08 | E-GEOD-34203 | biostudies-arrayexpress
2013-07-17 | E-GEOD-48940 | biostudies-arrayexpress
2010-06-01 | E-GEOD-21427 | biostudies-arrayexpress