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Host nasopharyngeal transcriptome analysis in a SARS-CoV-2 positive Italian cohort

ABSTRACT: The ongoing COVID-19 pandemic caused by SARS-CoV-2 has affected millions of people worldwide and has significant implications for public health. Host transcriptomics profiling provides comprehensive understanding of how the virus interacts with host cells and how the host responds to the virus. COVID-19 disease alters the host transcriptome, affecting cellular pathways and key molecular functions. To contribute to the global effort to understand the virus’s effect on host cell transcriptome, we have generated a dataset from nasopharyngeal swabs of 35 individuals infected with SARS-CoV-2 from the Campania region in Italy during the three outbreaks, with different clinical conditions. This dataset will help to elucidate the complex interactions among genes and can be useful in the development of effective therapeutic pathways

INSTRUMENT(S): Illumina NovaSeq 6000, RNA purity was determined by using NanoDrop spectrophotometer ND-2000 (Thermo Fischer Scientific) through the evaluation of the absorbance ratio A260/A280, none, ELITeInGenius SP RNA cartridge (ELITechGroup) via ELITeInGenius fully automated system (ELITechGroup)

ORGANISM(S): Homo sapiens

SUBMITTER: Carlo Ferravante

PROVIDER: E-MTAB-13028 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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