TRANSCRIPTOME ANALYSIS DURING THE METAMORPHOSIS OF THE ASCIDIAN CIONA INTESTINALIS

ABSTRACT: Tunicates, including ascidians, are recognized as the true “sister group” of vertebrates and are emerging as models to study the development and degeneration of central nervous system (CNS). Ascidian larvae have the typical chordate body plan that includes a dorsal neural tube. During their metamorphosis, a deep tissue reorganization takes place, with some tissues that degenerate while others develop to become functional during the adult life. The larval CNS also degenerates and most neurons disappear, making room to the formation of adult CNS. The genome of the ascidian Ciona intestinalis has been sequenced and annotated, with several CNS specific genes that have been characterized, revealing specification mechanisms shared with humans. These features make ascidian metamorphosis a good mo

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Ciona intestinalis

SUBMITTER: Cristina Battaglia 

PROVIDER: E-MTAB-13385 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress