Project description:To investigate changes to eRNA transcripts in the presence and the absence of lapatinib in OE19 cells, we performed KAS-seq on OE19 cells treat with 500 nM lapatinib for 1 day.
Project description:To investigate enhancer activity in OE19 cells, we performed ATAC_STARR-seq and CUT&Tag_STARR-seq using antibodies against H3K27ac, BRD4 and MED1 .
Project description:To investigate the effect on chromatin accessibility with reduced ERBB2 signalling in oesophageal adenocarcinoma, we performed ATAC-seq in OE19 cells treated with either siNT or siERBB2.