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Spatial transcriptomics (Visium, 10x Genomics) data for human Idiopathic Pulmonary Fibrosis (IPF) and control lung tissue

ABSTRACT: Visium (10x Genomics) spatially resolved transcriptomics data generated from normal and Idiopathic Pulmonary Fibrosis (IPF) lung parenchyma tissues collected from human donors. The fresh-frozen tissues that were analyzed were from four healthy control (HC) subjects and from four IPF patients. For each IPF patient, three different tissues were selected representing areas of mild (“B1”), moderate (“B2\") or severe (“B3”) fibrosis within the same donor, as determined by histological inspection of Hematoxylin and Eosin (H&E)-stained samples. Data from a total of 25 tissue sections, from 16 unique lung tissue blocks. The lung tissues were collected post-mortem (HC donors) or during lung transplant/resection (IPF patients) after obtaining informed consent. The study protocols were approved by the local human research ethics committee (HC: Lund, permit number Dnr 2016/317; IPF: Gothenburg, permit number 1026-15) and the samples are anonymized and cannot/should not be traced back to individual donors.

INSTRUMENT(S): NA, 2100 Bioanalyzer (Agilent); Axio Imager.Z2 (ZEISS), Mastercycler pro S Thermocyler (Eppendorf); 2100 Bioanalyzer (Agilent), Illumina NovaSeq 6000, CryoStar NX70 Cryostat (Epredia)

ORGANISM(S): Homo sapiens

SUBMITTER: Lovisa Franzén

PROVIDER: E-MTAB-14121 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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