Epigenetic and metabolic rewiring in metastatic pheochromocytomas and paragangliomas driven by SDHB mutations (DNA methylation data)

ABSTRACT: Pheochromocytomas and paragangliomas (PPGLs) arising in patients with SDHB mutations have a well-established predisposition to develop metastatic disease, but the molecular mechanisms underlying this aggressive behavior remain incompletely understood. We investigated how metastasis and SDHB mutation status contribute to the epigenetic landscape of PPGLs, aiming to disentangle their individual and combined effects on tumor progression. This dataset contains the DNA methylation data of the 34 PPGLs analysed in this study.

ORGANISM(S): Homo sapiens

SUBMITTER: Mario Fernandez Fraga 

PROVIDER: E-MTAB-15178 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress