Synergistic effects of TOR and proteasome pathways on the yeast transcriptome and cell growth

ABSTRACT: The experiments were designed to interrogate the genetic interaction relationship between the TOR signalling pathway and the UPS-proteasome pathway in gene expression and cell growth. Yeast cells (BY4742pdr5delta) were treated with the drug vehicle, MG132 (50uM), rapamycin (200ng/ml) or both drugs. Samples in triplicates were taken at 0, 1, 2 and 3hours after treatment. Transcriptome were assayed using Affimetrixs genechips (Yeast 2).

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Nianshu Zhang 

PROVIDER: E-MTAB-1550 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress