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Decidual NK cells Xiong et al 2013

ABSTRACT: Receptors of the KIR family on maternal Natural Killer cells in the decidua are believed to bind to Ligands such as HLA-C on trophoblast cells invading into the decidua from the placenta during early pregnancy. The resulting responses regulate the extent of trophoblast invasion. Genetic studies have implicated two members of the KIR family in particular as playing an important role: KIR2DL1 and KIR2DS1. The aim of this experiment was to determine what responses are generated when decidual NK cells bearing either KIR2DL1 or KIR2DS1 engage their HLA-C ligand.

ORGANISM(S): Homo sapiens

SUBMITTER: Andrew Sharkey

PROVIDER: E-MTAB-1784 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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