Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina HiSeq 2000
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S
SUBMITTER: Joseph Wade
PROVIDER: E-MTAB-1915 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Journal of bacteriology 20131122 3
Escherichia coli AraC is a well-described transcription activator of genes involved in arabinose metabolism. Using complementary genomic approaches, chromatin immunoprecipitation (ChIP)-chip, and transcription profiling, we identify direct regulatory targets of AraC, including five novel target genes: ytfQ, ydeN, ydeM, ygeA, and polB. Strikingly, only ytfQ has an established connection to arabinose metabolism, suggesting that AraC has a broader function than previously described. We demonstrate ...[more]