Pancreatic islet epigenomics reveals enhancer clusters that are enriched in Type 2 diabetes risk variants
Ontology highlight
ABSTRACT: We combined ChIP-seq of chromatin marks and key islet transcription factor with RNA-seq in human islets to map cis-regulatory networks in this primary tissue. The output of this project provides a reference map to dissect genetic variants that alter the susceptibility for Type 2 diabetes, and assist efforts to generate new beta-cells by transcriptional programming strategies
INSTRUMENT(S): Illumina Genome Analyzer IIx, Illumina HiSeq 2000
ORGANISM(S): Homo sapiens
SUBMITTER: Lorenzo Pasquali
PROVIDER: E-MTAB-1919 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
ACCESS DATA