Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Fallon Padraic
PROVIDER: E-MTAB-2100 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Amu Sylvie S Saunders Sean P SP Kronenberg Mitchell M Mangan Niamh E NE Atzberger Ann A Fallon Padraic G PG
The Journal of allergy and clinical immunology 20100320 5
<h4>Background</h4>Parasitic helminth infections of humans have been shown to suppress the immune response to allergens. Experimentally, infection of mice with the helminth Schistosoma mansoni prevents allergic airway inflammation and anaphylaxis via IL-10 and B cells.<h4>Objective</h4>To identify and characterize the specific helminth-induced regulatory B-cell subpopulation and determine the mechanism by which these regulatory B cells suppress allergic airway inflammation.<h4>Methods</h4>IL-10- ...[more]