Biomphalaria glabrata haemocytes vs ESPs
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ABSTRACT: During its life cycle, the helminth parasite Schistosoma mansoni uses the freshwater snail Biomphalaria glabrata as an intermediate host to reproduce asexually generating cercariae for infection of the human definitive host. Following invasion of the snail, the parasite develops from a miracidium to a mother sporocyst and releases excretory secretory products (ESPs) that likely influence the outcome of host infection. To better understand molecular interactions between these ESPs and the host snail defence system, we determined gene expression profiles of haemocytes from S. mansoni resistant or -susceptible strains of B. glabrata exposed in vitro to S. mansoni ESPs (20ug/ml) for 1 h, using a 5K B. glabrata cDNA microarray.
ORGANISM(S): Biomphalaria glabrata
SUBMITTER: Anne Lockyer
PROVIDER: E-MTAB-2135 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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