Hpr1 sumoylation mutant

ABSTRACT: To gain insight into the impact of THO complex sumoylation on gene expression in yeast S. cerevisiae, total RNAs were extracted from wt and hpr1-KR cells and transcriptome profiles were analyzed by Agilent microarrays. The hpr1 K-R mutant is a version of the hpr1 THO subunit in which lysines 60-65 were simultaneously mutated, which abrogated the sumoylation of the protein.

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Frederic Devaux 

PROVIDER: E-MTAB-2138 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress