Single cell derived clonal analysis of human glioblastoma links functional and genomic heterogeneity
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ABSTRACT: Single cell derived clones were extracted from four glioblastoma tumors using fluorescence activated cell sorting with CD15 and CD133 markers. Unsorted bulk tumors were also derived. Genotyping and copy number analysis was carried out for each tumor separately. Patient blood was used as control for three tumors while the fourth tumor had no blood available and a control cohort of 226 individuals was used for the latter (see Silversides, C.K., et al., Rare copy number variations in adults with tetralogy of Fallot implicate novel risk gene pathways. PLoS genetics, 2012. 8(8): p. e1002843.)
ORGANISM(S): Homo sapiens
SUBMITTER: Juri Reimand
PROVIDER: E-MTAB-2694 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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