Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of left ventricular myocardium after sham or TAC surgery in BL/6N and BL/6J mice

ABSTRACT: The most commonly used inbred mouse strain, C57BL/6J, lacks a functional nicotinamide nucleotide transhydrogenase (Nnt) and thus, is protected from pressure-overload-induced oxidative stress and heart failure. We screened for differential gene expression in left ventricular myocardium after sham/transverse aortic constriction (TAC) surgery in 10-12 weeks old mice from BL/6N (functional Nnt) and BL/6J (non-functional Nnt, missense of exons 7-11) strains.

ORGANISM(S): Mus musculus

SUBMITTER: Alexander Nickel 

PROVIDER: E-MTAB-2732 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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