Transcription profiling by high throughput sequencing of methamphetamine-sensitized and saline-control mouse nucleus accumbens
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina HiSeq 2000
ORGANISM(S): Mus musculus
SUBMITTER: Li Zhu
PROVIDER: E-MTAB-2843 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
mRNA changes in nucleus accumbens related to methamphetamine addiction in mice.
Zhu Li L Li Jiaqi J Dong Nan N Guan Fanglin F Liu Yufeng Y Ma Dongliang D Goh Eyleen L K EL Chen Teng T
Scientific reports 20161121
Methamphetamine (METH) is a highly addictive psychostimulant that elicits aberrant changes in the expression of microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) in the nucleus accumbens of mice, indicating a potential role of METH in post-transcriptional regulations. To decipher the potential consequences of these post-transcriptional regulations in response to METH, we performed strand-specific RNA sequencing (ssRNA-Seq) to identify alterations in mRNA expression and their alternative spli ...[more]
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