Unknown,Transcriptomics,Genomics,Proteomics

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Comparison of transcriptomic profiling between recovery and death group in H7N9 severe infection


ABSTRACT: Transcriptomic analysis confirms increased cellular activation in the patient recovery group. To identify molecular signatures correlated with H7N9 disease outcomes, we analysed the immune-related transcriptomes for PBMCs from 4 of the recovered (a73 d11, a134 d22, a20 d22, and a9 d21) and 4 of the fatal cases (a22 d22, a33 d21, a118 d19, and a131 d22). Total RNA was run on Affymetrix Human Gene ST 2.0 arrays and details of the probeset level normalisation and differential expression analysis are given in the Methods.

ORGANISM(S): Homo sapiens

SUBMITTER: Zhongfang Wang 

PROVIDER: E-MTAB-3005 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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