Unknown,Transcriptomics,Genomics,Proteomics

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ChIP-chip by array of yeast transcription factor binding sites under normal and heatshock conditions

ABSTRACT: An experiment was performed to determine the transcription factor binding site of yeast at room temperature and heat-shock growth conditions.

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Bryan Venters 

PROVIDER: E-MTAB-311 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Hundreds of different proteins regulate and implement transcription in Saccharomyces. Yet their interrelationships have not been investigated on a comprehensive scale. Here we determined the genome-wide binding locations of 200 transcription-related proteins, under normal and acute heat-shock conditions. This study distinguishes binding between distal versus proximal promoter regions as well as the 3' ends of genes for nearly all mRNA and tRNA genes. This study reveals (1) a greater diversity an  ...[more]

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