Ontology highlight
ABSTRACT:
INSTRUMENT(S): GenePix 4000B Microarray Scanner (Molecular Devices).
ORGANISM(S): Homo sapiens
SUBMITTER: Emanuela Guerra
PROVIDER: E-MTAB-3153 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Li Yan Y Melnikov Anatoliy A AA Levenson Victor V Guerra Emanuela E Simeone Pasquale P Alberti Saverio S Deng Youping Y
BMC cancer 20150519
<h4>Background</h4>DNA methylation regulates gene expression, through the inhibition/activation of gene transcription of methylated/unmethylated genes. Hence, DNA methylation profiling can capture pivotal features of gene expression in cancer tissues from patients at the time of diagnosis. In this work, we analyzed a breast cancer case series, to identify DNA methylation determinants of metastatic versus non-metastatic tumors.<h4>Methods</h4>CpG-island methylation was evaluated on a 56-gene canc ...[more]