Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

The propagation of perturbations in shuffled bacterial gene networks


ABSTRACT: This dataset contains transcription profiles of TOP10 E.coli transformed with 85 rewired network plasmids first described in: Evolvability and hierarchy in rewired bacterial gene networks. Nature 452:840-5 (2008). The data are described and analysed in an accompanying paper Baumstark et al.,The propagation of perturbations in shuffled bacterial gene networks (Submitted, 2015). 260 raw data microarrays are provided in total, representing biological triplicates (a,b and c; independent colonies grown from the same transformation, under standard growth conditions; LB, 16h). This is done for each of 255 promoter-ORF constructs (e.g. appY-crp, etc.) and 5 control construct microarrays (empty plasmid; Co). Co controls are provided for comparison, to show the relative effect of the rewiring gen

ORGANISM(S): Escherichia coli str. K-12 substr. MG1655

SUBMITTER: Mark Isalan 

PROVIDER: E-MTAB-3233 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress