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Complex gene flow boundaries among sympatric Anopheles vector mosquito populations revealed by genome-wide SNP genotyping

ABSTRACT: Complex gene flow boundaries among sympatric Anopheles vector mosquito populations revealed by genome-wide SNP genotyping.

Normalized data is provided in archive E-MTAB-338.additional.zip on the FTP site for this experiment.

ORGANISM(S): Anopheles gambiae

SUBMITTER: Seth Redmond

PROVIDER: E-MTAB-338 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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SNP genotyping defines complex gene-flow boundaries among African malaria vector mosquitoes.

Neafsey D E DE Lawniczak M K N MKN Park D J DJ Redmond S N SN Coulibaly M B MB Traoré S F SF Sagnon N N Costantini C C Johnson C C Wiegand R C RC Collins F H FH Lander E S ES Wirth D F DF Kafatos F C FC Besansky N J NJ Christophides G K GK Muskavitch M A T MAT

Science (New York, N.Y.) 20101001 6003

Mosquitoes in the Anopheles gambiae complex show rapid ecological and behavioral diversification, traits that promote malaria transmission and complicate vector control efforts. A high-density, genome-wide mosquito SNP-genotyping array allowed mapping of genomic differentiation between populations and species that exhibit varying levels of reproductive isolation. Regions near centromeres or within polymorphic inversions exhibited the greatest genetic divergence, but divergence was also observed ...[more]

PMID: 20966254

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