Dataset Information
Phenome analysis of Mycoplasma pneumoniae
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina HiSeq 2500
ORGANISM(S): Mycoplasma pneumoniae M129
SUBMITTER: Eva Yus
PROVIDER: E-MTAB-3771 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Impact of genome reduction on bacterial metabolism and its regulation.
Science (New York, N.Y.) 20091101 5957
To understand basic principles of bacterial metabolism organization and regulation, but also the impact of genome size, we systematically studied one of the smallest bacteria, Mycoplasma pneumoniae. A manually curated metabolic network of 189 reactions catalyzed by 129 enzymes allowed the design of a defined, minimal medium with 19 essential nutrients. More than 1300 growth curves were recorded in the presence of various nutrient concentrations. Measurements of biomass indicators, metabolites, a ...[more]
