Illumina HiSeq next -generation sequencing of telomere fusion amplicons purified from crisis-stage MCR5HPVE6E7 and TALEN-transfected HCT116 cell lines at 48 and 120 hours post-transfection.
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ABSTRACT: We sequenced and characterised inter-chromosomal and intra-chromosomal telomere fusions amplified from crisis-stage MCR5HPVE6E7 fibroblasts and DNA repair-compromised HCT116 cell lines nucleofected with plasmids encoding TALEN pairs to induce targeted cleavage at the 17p telomere.
INSTRUMENT(S): Illumina HiSeq 2500, Illumina HiSeq 2000
ORGANISM(S): Homo sapiens
SUBMITTER: Kevin Ashelford
PROVIDER: E-MTAB-3811 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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