Transcriptomic analyses of primary uveal melanomas

ABSTRACT: SF3B1 is coding an essential splicing factor. This gene was found recurrently mutated in uveal melanoma. To understand the consequences of these hotspot SF3B1 mutations, we performed high coverage RNA-seq on 74 primary uveal melanomas, which were treated by primary enucleation. We analyzed data for aberrant splicing in relation with SF3B1 status.

INSTRUMENT(S): Illumina HiSeq 2500

ORGANISM(S): Homo sapiens

SUBMITTER: Marc-Henri Stern 

PROVIDER: E-MTAB-4097 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress