Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina Genome Analyzer IIx
ORGANISM(S): Mus musculus
SUBMITTER: Vedran Franke
PROVIDER: E-MTAB-4775 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Karlic Rosa R Ganesh Sravya S Franke Vedran V Svobodova Eliska E Urbanova Jana J Suzuki Yutaka Y Aoki Fugaku F Vlahovicek Kristian K Svoboda Petr P
DNA research : an international journal for rapid publication of reports on genes and genomes 20170401 2
The oocyte-to-embryo transition (OET) transforms a differentiated gamete into pluripotent blastomeres. The accompanying maternal-zygotic RNA exchange involves remodeling of the long non-coding RNA (lncRNA) pool. Here, we used next generation sequencing and de novo transcript assembly to define the core population of 1,600 lncRNAs expressed during the OET (lncRNAs). Relative to mRNAs, OET lncRNAs were less expressed and had shorter transcripts, mainly due to fewer exons and shorter 5' terminal ex ...[more]