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Genome-Wide Expression Profiles in Very Low Birth Weight Infants With Neonatal Sepsis

ABSTRACT: Bacterial sepsis is associated with high morbidity and mortality in preterm infants. However, diagnosis of sepsis and identification of the causative agent remains challenging. Our aim was to determine genome-wide expression profiles of very low birth weight (VLBW) infants with and without bacterial sepsis and assess differences.

ORGANISM(S): Homo sapiens

SUBMITTER: Eva Serna

PROVIDER: E-MTAB-4785 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Genome-wide expression profiles in very low birth weight infants with neonatal sepsis.

Cernada María M Serna Eva E Bauerl Christine C Collado María Carmen MC Pérez-Martínez Gaspar G Vento Máximo M

Pediatrics 20140407 5

<h4>Background</h4>Bacterial sepsis is associated with high morbidity and mortality in preterm infants. However, diagnosis of sepsis and identification of the causative agent remains challenging. Our aim was to determine genome-wide expression profiles of very low birth weight (VLBW) infants with and without bacterial sepsis and assess differences.<h4>Methods</h4>This was a prospective observational double-cohort study conducted in VLBW (<1500 g) infants with culture-positive bacterial sepsis an ...[more]

PMID: 24709930

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