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Transcriptional responses in bovine skin during blood feeding of the cattle tick, Rhipicephalus microplus.

ABSTRACT: We examined gene expression induced by Rhipicephalus microplus bites on host skin of tick-resistant and tick-susceptible breeds of bovines, Nelore and Holstein respectively, when they underwent a primary infestation.

ORGANISM(S): Bos taurus

SUBMITTER: SANDRA REGINA COSTA MARUYAMA

PROVIDER: E-MTAB-4908 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Immune and biochemical responses in skin differ between bovine hosts genetically susceptible and resistant to the cattle tick Rhipicephalus microplus.

Franzin Alessandra Mara AM Maruyama Sandra Regina SR Garcia Gustavo Rocha GR Oliveira Rosane Pereira RP Ribeiro José Marcos Chaves JM Bishop Richard R Maia Antônio Augusto Mendes AA Moré Daniela Dantas DD Ferreira Beatriz Rossetti BR Santos Isabel Kinney Ferreira de Miranda IK

Parasites & vectors 20170131 1

<h4>Background</h4>Ticks attach to and penetrate their hosts' skin and inactivate multiple components of host responses in order to acquire a blood meal. Infestation loads with the cattle tick, Rhipicephalus microplus, are heritable: some breeds carry high loads of reproductively successful ticks, whereas in others, few ticks feed and reproduce efficiently.<h4>Methods</h4>In order to elucidate the mechanisms that result in the different outcomes of infestations with cattle ticks, we examined glo ...[more]

PMID: 28143523

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