Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

192 adult acute lymphoblastic leukemia (ALL) cases characterized on the Affymetrix Human Genome U133 Plus 2.0 Microarray


ABSTRACT: Acute lymphoblastic leukemia (ALL) is characterized by the accumulation of somatic genetic alterations in B- or T-lymphoid precursor cells eventually resulting in overt leukemia. Contrary to paediatric ALL, its adult counterpart is rather scarcely researched. Early studies demonstrated that gene expression profiling (GEP) is a valuable tool for subgroup identification and risk stratification. This submission of 192 ALL (137 B-cell ALL [B-ALL] and 55 T-cell ALL [T-ALL]) cases characterized on gene expression microarrays serves as a repository for multiple studies examining the leukemogenic mechanisms underlying overt ALL establishment. After informed consent, bone marrow aspirates or peripheral blood samples of a representative cohort of 192 adult ALL patients were collected. Eligible pa

ORGANISM(S): Homo sapiens

SUBMITTER: Peter Valk 

PROVIDER: E-MTAB-5035 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress