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Retinoic acid mediated neural and mesoderm specification during vertebrate trunk development

ABSTRACT: Neuromesodermal progenitors are located in the caudal lateral epiblast region of embryos and are important for the generation of spinal cord and somite tissue that forms the vertebrate body. In this study we use single cell transcriptomics to define the molecular signature of in vivo and in vitro NMPs and reverse engineer the mechanism that regulates their differentiation towards the neural and mesodermal lineage.

INSTRUMENT(S): Illumina HiSeq 2500, Linux computer, Linux Beowulf cluster; AMD Opteron Linux Beowulf cluster; AMD Opteron 6168

ORGANISM(S): Mus musculus

SUBMITTER: James Briscoe

PROVIDER: E-MTAB-5208 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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