Unknown,Transcriptomics,Genomics,Proteomics

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Microarray data of foetal liver Lin- cKit+ cells obtained from Fh1-deficient and control 14.5 dpc mouse embryos


ABSTRACT: Haematopoiesis-specific Fh1 deletion causes lethal foetal liver haematopoietic defects. To understand the impact of Fh1 deletion on the transcriptome of foetal liver Lin- c-Kit+ cells we preformed microarray analysis. To conditionally delete Fh1 in the foetal liver we used the Vav-iCre recombinase and a Fh1 flox allele. Foetal livers were dissected and used to generate a single cell suspension. Lin- c-Kit+ cells were FACS sorted and lysed for total RNA preparation. We collected samples from 4 experimental animals (Fh1 fl/fl; Vav-iCre/+) and 3 control animals (Fh1 fl/fl).

ORGANISM(S): Mus musculus

SUBMITTER: Marcos Morgan 

PROVIDER: E-MTAB-5425 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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