Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of colon cancer tumor and normal biopsies from a series of patients to identify molecular biomarkers


ABSTRACT: Expression profiling studies on colon cancer comparing tumoral and normal biopsies from a series of patients in order to identify molecular biomarkers.

ORGANISM(S): Homo sapiens

SUBMITTER: Massimo Carella 

PROVIDER: E-MTAB-57 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

On the statistical assessment of classifiers using DNA microarray data.

Ancona N N   Maglietta R R   Piepoli A A   D'Addabbo A A   Cotugno R R   Savino M M   Liuni S S   Carella M M   Pesole G G   Perri F F  

BMC bioinformatics 20060819


<h4>Background</h4>In this paper we present a method for the statistical assessment of cancer predictors which make use of gene expression profiles. The methodology is applied to a new data set of microarray gene expression data collected in Casa Sollievo della Sofferenza Hospital, Foggia--Italy. The data set is made up of normal (22) and tumor (25) specimens extracted from 25 patients affected by colon cancer. We propose to give answers to some questions which are relevant for the automatic dia  ...[more]

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