Amplification of 1q32.1 refines the molecular classification of endometrial carcinoma: SNP array
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ABSTRACT: The experiment aimed at refining the classification of endometrial cancer by profiling somatic copy number aberrations (SCNAs). SCNAs affecting chromosome 1q32.1 significantly correlated with worse survival and functional validation of a plausible oncogene showed MDM4 as an oncogenic driver in 1q32.1 and a putative therapeutic target for NSMP ECs.
ORGANISM(S): Homo sapiens
SUBMITTER: Bram Boeckx
PROVIDER: E-MTAB-5908 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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