Amplification of 1q32.1 refines the molecular classification of endometrial carcinoma: SNP array

ABSTRACT: The experiment aimed at refining the classification of endometrial cancer by profiling somatic copy number aberrations (SCNAs). SCNAs affecting chromosome 1q32.1 significantly correlated with worse survival and functional validation of a plausible oncogene showed MDM4 as an oncogenic driver in 1q32.1 and a putative therapeutic target for NSMP ECs.

ORGANISM(S): Homo sapiens

SUBMITTER: Bram Boeckx 

PROVIDER: E-MTAB-5908 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress